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Neuro-Oncology

Clinical Trials

Neuro-Oncology Protocol Information

All Clinical Trials Information

Protocol Number Title Study Status PI Website Section
Phase 1
10C0219 A Phase I Trial of Lenalidomide and Radiotherapy in Children with Diffuse Intrinsic Pontine Gliomas and High-grade Gliomas Currently Accruing Warren, Kathy
Link Neuro-Oncology
10C0220 Phase I Trial to Evaluate the Safety, Activity and Pharmacokinetics of Marqibo® (Vincristine Sulfate Liposomes Injection) in Children and Adolescents with Refractory Cancer Currently Accruing Shah, Nirali
Link Solid Tumors
Neuro-Oncology
Hematologic Diseases
11C0047 Phase I trial and pharmacokinetic study of the oral platinum analog satraplatin in children and young adults with refractory solid tumors including brain tumors Not Currently Accruing Widemann, Brigitte
Link Solid Tumors
Neuro-Oncology
Pharmacology and Experimental Therapeutics
11C0191 Phase 1 and Pharmacokinetic Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma Currently Accruing Warren, Kathy
Link Neuro-Oncology
13C0042 ADVL1211: A Phase I Study of XL184 (Cabozantinib, IND# 116059) in Children and Adolescents with Recurrent or Refractory Solid Tumors, Including CNS Tumors Currently Accruing Widemann, Brigitte
  Solid Tumors
Pharmacology and Experimental Therapeutics
Neuro-Oncology
Phase 1 & 2
12C0213 PBTC-033 A Phase I/II Study of ABT-888, an Oral Poly (ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children with Newly Diagnosed Diffuse Pontine Glioma (DIPG) Currently Accruing Warren, Kathy
  Neuro-Oncology
Phase 2
12C0058 A Phase II Study of Everolimus (RAD001) for Children with Neurofibromatosis Type-1 and Chemotherapy-Refractory Radiographic Progressive Low-Grade Gliomas Currently Accruing Warren, Kathy
Link Neuro-Oncology
Neurofibromatosis
12C0136 A Phase II Randomized Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas Currently Accruing Warren, Kathy
Link Neuro-Oncology
13C0191 A Molecular Biology and Phase II Study of Imetelstat (GRN163L) in Children with Recurrent High-Grade Glioma, Ependymoma and Diffuse Intrinsic Pontine Glioma Not Currently Accruing Warren, Kathy
Link Neuro-Oncology
Other
03C0278 A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI) Currently Accruing Warren, Kathy
Link Neuro-Oncology
06C0219 An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors Currently Accruing Warren, Kathy
Link Neuro-Oncology
14C0079 An Exploratory Study of Voicing My CHOiCES as a Tool for Advanced Care Planning in Young Adults with Metastatic, Recurrent, or Progressive Cancer Currently Accruing Wiener, Lori
Link Hematologic Diseases
Medullary Thyroid Carcinoma
Neuro-Oncology
Neurofibromatosis
Solid Tumors
Psychosocial
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