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Neuro-Oncology

Clinical Trials

Neuro-Oncology Protocol Information

All Clinical Trials Information

Protocol Number Title Study Status PI Website Section
Phase 1
10C0219 A Phase I Trial of Lenalidomide and Radiotherapy in Children with Diffuse Intrinsic Pontine Gliomas and High-grade Gliomas Currently Accruing Warren, Kathy
Link Neuro-Oncology
10C0220 Phase I Trial to Evaluate the Safety, Activity and Pharmacokinetics of Marqibo® (Vincristine Sulfate Liposomes Injection) in Children and Adolescents with Refractory Cancer Currently Accruing Wayne, Alan
Link Solid Tumors
Neuro-Oncology
Hematologic Diseases
11C0047 Phase I trial and pharmacokinetic study of the oral platinum analog satraplatin in children and young adults with refractory solid tumors including brain tumors Currently Accruing Widemann, Brigitte
Link Solid Tumors
Neuro-Oncology
Pharmacology and Experimental Therapeutics
11C0191 Phase 1 and Pharmacokinetic Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma Currently Accruing Warren, Kathy
Link Neuro-Oncology
13C0042 ADVL1211: A Phase I Study of XL184 (Cabozantinib, IND# 116059) in Children and Adolescents with Recurrent or Refractory Solid Tumors, Including CNS Tumors Currently Accruing Widemann, Brigitte
  Solid Tumors
Pharmacology and Experimental Therapeutics
Neuro-Oncology
Phase 1 & 2
12C0213 PBTC-033 A Phase I/II Study of ABT-888, an Oral Poly (ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children with Newly Diagnosed Diffuse Pontine Glioma (DIPG) Open to Accrual Warren, Kathy
  Neuro-Oncology
Phase 2
12C0058 A Phase II Study of Everolimus (RAD001) for Children with Neurofibromatosis Type-1 and Chemotherapy-Refractory Radiographic Progressive Low-Grade Gliomas Currently Accruing Warren, Kathy
Link Neuro-Oncology
Neurofibromatosis
12C0136 A Phase II Randomized Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas Currently Accruing Warren, Kathy
Link Neuro-Oncology
Other
03C0278 A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI) Open to Accrual Warren, Kathy
Link Neuro-Oncology
06C0219 An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients with Central Nervous System Tumors Currently Accruing Warren, Kathy
Link Neuro-Oncology
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